Cart
sales@molnova.com
Home -
Products -
Membrane Transporter/Ion Channel -
TRP/TRPV Channel -
HC067047 Hydrochloride(883031-03-6 free base)
HC067047 Hydrochloride(883031-03-6 free base)
CAS No. 1481646-76-7
HC067047 Hydrochloride(883031-03-6 free base)( —— )
Catalog No. M23636 CAS No. 1481646-76-7
HC-067047 hydrochloride is a potent and selective TRPV4 antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 272 | In Stock |
|
| 10MG | 408 | In Stock |
|
| 25MG | 672 | In Stock |
|
| 50MG | 945 | In Stock |
|
| 100MG | 1278 | In Stock |
|
| 500MG | 2547 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameHC067047 Hydrochloride(883031-03-6 free base)
-
NoteResearch use only, not for human use.
-
Brief DescriptionHC-067047 hydrochloride is a potent and selective TRPV4 antagonist.
-
DescriptionHC-067047 hydrochloride is a potent and selective TRPV4 antagonist. HC-067047 hydrochloride reversibly inhibited currents through the human, rat, and mouse TRPV4 orthologs with IC50 values of 486 nM, 133nM, and 17 nM, respectively.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayMembrane Transporter/Ion Channel
-
TargetTRP/TRPV Channel
-
RecptorTRPV4
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1481646-76-7
-
Formula Weight507.98
-
Molecular FormulaC26H29ClF3N3O2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(C1=C(C)N(CCCN2CCOCC2)C(C3=CC=CC=C3)=C1)NC4=CC=CC(C(F)(F)F)=C4.[H]Cl
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Xing Y , Ming J , Liu T , et al. Decreased Expression of TRPV4 Channels in HEI-OC1 Cells Induced by High Glucose Is Associated with Hearing Impairment[J]. Yonsei medical journal, 2018, 59(9).
molnova catalog
related products
-
Elismetrep
Elismetrep (MT-8554) is an orally available TRPM8 inhibitor with potential analgesic activity for the study of vasomotor symptoms in postmenopausal women.
-
JC-229
JC-229 is a potent and selective TbRPA1 inhibitor that can inhibit RPA1 in Trypanosoma brucei. JC-229 can be used to study human African Trypanosomiasis (HAT).
-
Pyr3
Pyr3 is a selective transient receptor potential canonical channel 3 inhibitor. Pyr3 inhibits TRPC3-mediated Ca2+ influx in a dose-dependent manner(IC50 = 700 nM).
